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Hyperglycaemic hyperosmolar state and cerebral thrombophlebitis in paediatrics: A case report
Maud Injeyan1, Sabine Baron1,2, Benjamin Lauzier3,4
1Department of Pediatrics, CHU de Nantes, Nantes, France.
Endocrinology, Diabetes & Metabolism
|February 1, 2023
Summary
Hyperglycaemic hyperosmolar state (HHS) can occur in type 1 diabetes, especially after consuming sugary drinks. This case shows HHS can lead to cerebral venous thrombosis in children, emphasizing gradual osmolarity reduction during treatment.
Area of Science:
- Pediatrics
- Endocrinology
- Neurology
Background:
- Hyperglycaemic hyperosmolar state (HHS) is a serious complication of diabetes mellitus.
- While known in type 2 diabetes, HHS can also present severely in type 1 diabetes, particularly with high-sugar fluid intake.
- HHS management is complex and associated with severe complications, including cerebral venous thrombosis.

