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Updated: Aug 12, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Advances of Antimicrobial Peptide-Based Biomaterials for the Treatment of Bacterial Infections
Guoyu Li1, Zhenheng Lai1, Anshan Shan1
1The Institute of Animal Nutrition, Northeast Agricultural University, Harbin, 150030, P. R. China.
Abstract:
Owing to the increase in multidrug-resistant bacterial isolates in hospitals globally and the lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have increased substantially. There is thus an urgent need to develop new antimicrobial drugs and their related formulations. In recent years, natural antimicrobial peptides (AMPs), AMP optimization, self-assembled AMPs, AMP hydrogels, and biomaterial-assisted delivery of AMPs have shown great potential in the treatment of bacterial infections. In this review, it is focused on the development prospects and shortcomings of various AMP-based biomaterials for treating animal model infections, such as abdominal, skin, and eye infections. It is hoped that this review will inspire further innovations in the design of AMP-based biomaterials for the treatment of bacterial infections and accelerate their commercialization.
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