[Antioxidants--effective pathogenetic agents in the combined therapy of pulmonary tuberculosis]

The use of anti-oxidants (alpha-tocopherol and sodium thiosulphate in multimodality therapy of patients with infiltrative pulmonary tuberculosis raised therapeutic efficacy promoting elimination of signs of tuberculous intoxication, the onset of bacteria elimination, disintegration cavity closing, and a decrease in the frequency of residual changes. The advantage of alpha-tocopherol was shown in its administration to patients with infiltrative tuberculosis with the prevailing productive tissue reactions. alpha-tocopherol prevented the occurrence of noticeable respiratory insufficiency contributing to its elimination in patients with fibrocavernous tuberculosis.