Demographic and Clinical Predictors of Pharmacist-Administered Pediatric Influenza Immunization

Dana M Gates1, Steven A Cohen2, Kelly Orr1

  • 1College of Pharmacy, University of Rhode Island, Kingston, RI, USA.

Insights

Pharmacists are increasingly administering pediatric influenza vaccines, driven by older children, fewer age restrictions, and prior pharmacy vaccination. This trend is amplified by the COVID-19 pandemic and expanded pharmacist authority.

Area of Science:

  • Public Health
  • Pharmacy Practice
  • Pediatric Medicine

Background:

  • Pediatricians' offices are traditional sites for childhood influenza immunizations.
  • Pharmacists are emerging as key immunizers, especially with expanded authority under the Public Readiness and Emergency Preparedness (PREP) Act.
  • The COVID-19 pandemic has highlighted the importance of accessible vaccination services.

Purpose of the Study:

  • To identify demographic and clinical factors predicting pharmacist-administered pediatric influenza vaccination.
  • To compare vaccination in pharmacies versus pediatrician offices.
  • To understand trends in pediatric influenza immunization delivery.

Main Methods:

  • Utilized the de-identified Optum Clinformatics™ Data Mart database.
  • Analyzed procedural codes for pediatric influenza vaccinations during the 2016-2017 season.
  • Employed logistic regression to determine significant predictors of vaccination location.

Main Results:

  • Identified 336,841 pediatric influenza vaccinations: 5.2% by pharmacists, 94.8% in pediatrician offices.
  • Key predictors for pharmacy vaccination included older pediatric age (13-17 years), states with fewer age restrictions, prior pharmacy vaccination, and routine health exams.
  • Geographic region also influenced vaccination location.

Conclusions:

  • Older pediatric age, lenient state-level age restrictions for pharmacy vaccination, and prior pharmacy influenza vaccination are primary drivers for pharmacist-administered vaccines.
  • The COVID-19 pandemic and PREP Act may lead to sustained shifts in pediatric vaccination practices, with pharmacists playing a larger role.
  • Future pediatric COVID-19 vaccine availability could further increase pharmacist involvement in childhood immunizations.

Related Concept Videos

Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.1K
Vaccinations01:51

Vaccinations

Overview
45.1K
Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
331
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.3K
Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance01:23

Nonlinear Pharmacokinetics: Dependence of Elimination Half-Life and Dose Clearance

The elimination half-life and drug clearance of drugs following nonlinear kinetics can vary with dosage. The Michaelis-Menten parameters and drug concentration influence these factors. As the dose increases, the elimination half-life tends to lengthen, resulting in a reduction in clearance and a disproportionately larger area under the curve. The total clearance can be derived from the Michaelis-Menten equation for drugs following a one-compartment model.
A study on guinea pigs examined the...
240
Factors Affecting Protein-Drug Binding: Patient-Related Factors01:29

Factors Affecting Protein-Drug Binding: Patient-Related Factors

Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
90