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Published on: December 17, 2021
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Ocular tuberculosis presenting with a conjunctival granuloma.
H Ben Amor1, H Krifa2, M Mefteh2
1Service d'ophtalmologie, CHU de Fattouma-Bourguiba, faculté de médecine, université de Monastir, 5019 Monastir, Tunisia; Faculté de médecine, université de Monastir, Monastir, Tunisia.
Journal Francais D'Ophtalmologie
|February 1, 2023
Summary
Tuberculosis can cause chronic conjunctivitis, presenting as a vascularized lesion. Prompt biopsy and antituberculosis therapy led to complete resolution in an 18-year-old female patient.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Pathology
Background:
- Unilateral chronic conjunctivitis can be challenging to diagnose and treat.
- Ocular trauma may predispose individuals to certain infections.
Observation:
- An 18-year-old female presented with a 3-month history of left eye tearing and redness post-trauma.
- Slit-lamp examination revealed a vascularized, polypoidal conjunctival lesion with micronodules.
- Biopsy showed tuberculoid granulomas with giant cells and necrosis.
Findings:
- Histopathology confirmed granulomatous inflammation consistent with tuberculosis.
- A positive Mantoux test (15mm induration) supported the diagnosis.
- Antituberculosis therapy resulted in complete resolution of conjunctival lesions within 3 months.
Implications:
- Mycobacterium tuberculosis should be considered in recalcitrant unilateral conjunctivitis.
- Conjunctival mass biopsy is crucial for definitive diagnosis.
- Early diagnosis and treatment of ocular tuberculosis can prevent long-term complications.
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