Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vaccinations01:51

Vaccinations

45.1K
Overview
45.1K
Development of Immunocompetence01:22

Development of Immunocompetence

405
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
405
Humoral Immune Responses01:36

Humoral Immune Responses

73.7K
Overview
73.7K
Active versus Passive Immunity01:31

Active versus Passive Immunity

1.9K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
1.9K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

862
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
862

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Global Incidence, Risk Factors, and Trends of Pharyngeal Cancer by Anatomical Sites: A Systematic Analysis of Cancer Registries.

Cancer reports (Hoboken, N.J.)·2026
Same author

Factors Affecting Implementation of the EQUIPPED Medication Safety Program for Older Veterans in the Emergency Department: A Qualitative Analysis.

Journal of the American Geriatrics Society·2026
Same author

Maternal-neonatal vitamin D gradient at birth in Ilorin, Nigeria: a comparative cross-sectional study.

Maternal health, neonatology and perinatology·2026
Same author

Escaping the metric-driven governance trap in global health: how DALYs and coverage indicators mislead policymakers in LMICs.

International journal for equity in health·2026
Same author

Regional inequalities and temporal trends in maternal disorders across sub-Saharan Africa, 1990-2023: a systematic analysis of the global burden of disease 2023 data.

Archives of public health = Archives belges de sante publique·2026
Same author

Mapping antimicrobial resistance interventions in ASEAN countries: a scoping review of implementation patterns, One Health integration, and evidence gaps.

Tropical medicine and health·2026

Related Experiment Video

Updated: Aug 12, 2025

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
16:56

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Published on: August 30, 2014

17.1K

Achieving herd immunity in South America.

Don Eliseo Lucero-Prisno1,2,3, Deborah Oluwaseun Shomuyiwa4, Creuza Rachel Vicente5,6

  • 1Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.

Global Health Research and Policy
|February 2, 2023
PubMed
Summary

South America achieved a high COVID-19 vaccination rate, demonstrating public trust and acceptance of vaccines. Continued efforts in vaccine supply, equity, and local production are key to advancing population protection and potentially achieving herd immunity.

Keywords:
COVID-19Herd immunityPandemicPopulation healthSouth AmericaVaccination

More Related Videos

Immunization of Alpacas Lama pacos with Protein Antigens and Production of Antigen-specific Single Domain Antibodies
05:27

Immunization of Alpacas Lama pacos with Protein Antigens and Production of Antigen-specific Single Domain Antibodies

Published on: January 26, 2019

23.7K
Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
13:00

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

3.7K

Related Experiment Videos

Last Updated: Aug 12, 2025

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
16:56

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections

Published on: August 30, 2014

17.1K
Immunization of Alpacas Lama pacos with Protein Antigens and Production of Antigen-specific Single Domain Antibodies
05:27

Immunization of Alpacas Lama pacos with Protein Antigens and Production of Antigen-specific Single Domain Antibodies

Published on: January 26, 2019

23.7K
Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus
13:00

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

3.7K

Area of Science:

  • Epidemiology
  • Public Health
  • Immunology

Background:

  • South America faced significant challenges during the COVID-19 pandemic, with high infection rates and strained healthcare systems.
  • The region has since implemented robust public health strategies to manage the ongoing pandemic.
  • A strong vaccination culture and public confidence have been pivotal in the region's response.

Purpose of the Study:

  • To analyze the COVID-19 pandemic management strategies in South America.
  • To highlight the region's success in achieving high vaccination rates.
  • To identify factors contributing to vaccine acceptance and explore pathways toward herd immunity.

Main Methods:

  • Observational analysis of regional pandemic response data.
  • Review of vaccination coverage statistics and public health system performance.
  • Assessment of factors influencing vaccine acceptance and trust.

Main Results:

  • South America has become the region with the highest global vaccination rate, with over 76% of the population fully vaccinated.
  • The high vaccination uptake reflects strong public trust in vaccination and public health systems.
  • Herd immunity is not yet feasible but high vaccination rates indicate acceptance of vaccination as a population protection strategy.

Conclusions:

  • Leveraging deep-rooted vaccination culture and public confidence has been crucial for South America's pandemic response.
  • Achieving herd immunity requires continued vaccine supply, equitable access, improved acceptance, and trust.
  • Local vaccine production, infrastructure investment, and international collaboration are vital for future population safety and pandemic preparedness.