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A decision-making algorithm proposal for PICCs and midlines insertion in patients with advanced kidney disease: A
Arianna Bartoli1, Maurizio Gallieni1,2, Chiara Cogliati1
1Department of Biomedical and Clinical Sciences "Luigi Sacco," University of Milan, Luigi Sacco Hospital, Milan, Italy.
Charlson Comorbidity Index (CCI) and Beclap score effectively predict 2-year mortality in patients with peripherally inserted central catheters (PICCs) or Midlines. These scores can guide vascular access device decisions in chronic kidney disease (CKD) patients.
Area of Science:
- Nephrology
- Vascular Access
- Medical Informatics
Background:
- Current guidelines recommend against peripherally inserted vascular access devices (PVADs) in patients with estimated glomerular filtration rate (eGFR) <45 mL/min.
- Severe chronic kidney disease (CKD) often presents a poor prognosis, necessitating careful consideration of treatment risks and benefits.
Purpose of the Study:
- To assess the 2-year mortality in patients with PICCs or Midlines using the Charlson Comorbidity Index (CCI) and Beclap score.
- To determine if CCI and Beclap scores can guide PVAD implantation decisions in CKD patients with high predicted mortality.
Main Methods:
- A retrospective analysis of 131 patients with PICCs or Midlines inserted between October 2018 and November 2019.
- Calculation of CCI, Beclap score, and eGFR at catheter insertion, followed by a 2-year mortality assessment.
Main Results:
- The 2-year mortality rate was 57.3% among the enrolled patients.
- Beclap score cutoff of 15 and CCI cutoff of 5 demonstrated good sensitivity and specificity in predicting mortality across different patient subgroups, including those with eGFR <45 mL/min.
Conclusions:
- CCI and Beclap score are reliable predictors of 2-year mortality.
- These scores can aid clinicians in vascular access device selection for CKD patients, offering an alternative to relying solely on renal function.
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