Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Meningoencephalitis following enucleation for cryptococcal endophthalmitis.

L W Birkmann, D R Bennett

    Annals of Neurology
    |November 1, 1978
    PubMed
    Summary

    A penetrating eye injury led to cryptococcal endophthalmitis and subsequent meningoencephalitis. The optic nerve sheath is a likely pathway for fungal brain infection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Are IVC filters required in combat support hospitals?

    Journal of the Royal Army Medical Corps·2010
    Same author

    Zinc toxicity following massive coin ingestion.

    The American journal of forensic medicine and pathology·1997
    Same author

    Practical issues when confronting the patient who refuses blood transfusion therapy.

    American journal of clinical pathology·1997
    Same author

    The effect of misdiagnosis and delay in diagnosis on clinical outcome in melanomas of the foot.

    Journal of the American College of Surgeons·1994
    Same author

    A phenothiazine derivative reduces rat brain damage after global or focal ischemia.

    Stroke·1992
    Same author

    Happiness revisited.

    Postgraduate medicine·1990

    Area of Science:

    • Ophthalmology
    • Neurology
    • Infectious Diseases

    Background:

    • Cryptococcal endophthalmitis can arise from penetrating ocular trauma.
    • Fungal infections of the central nervous system (CNS) pose significant diagnostic and therapeutic challenges.

    Observation:

    • A patient presented with meningoencephalitis nine months post-enucleation of the right eye.
    • The enucleation was necessitated by cryptococcal endophthalmitis, confirmed after a penetrating injury.

    Findings:

    • The clinical course suggests a delayed CNS manifestation of Cryptococcus neoformans infection.
    • The optic nerve subarachnoid sheath is hypothesized as the route of fungal dissemination to the CNS.

    Implications:

    • This case highlights the potential for late-onset CNS cryptococcosis following ocular injury.
    • Understanding fungal spread via the optic nerve is crucial for managing similar infections.
    • Early recognition and treatment of ocular fungal infections may prevent severe neurological sequelae.

    Related Experiment Videos