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Single-stage Dynamic Reanimation of the Smile in Irreversible Facial Paralysis by Free Functional Muscle Transfer
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Facial Nerve Palsy as Complication in COVID-19 Associated Mucormycosis: A Case Series

Prashanthi Reddy1, Ajay Parihar1, Renu Singh1

  • 1Department of Oral Medicine and Radiology, Government College of Dentistry, Indore, IND.

Cureus
|February 2, 2023
PubMed

Insights

Mucormycosis, a severe fungal infection, surged during COVID-19. Early diagnosis of rhino-cerebral mucormycosis is crucial to reduce high mortality rates, especially with cranial nerve complications.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Ophthalmology

Background:

  • Mucormycosis is a life-threatening opportunistic fungal infection with high mortality.
  • Rhino-cerebral mucormycosis (RCM) is a significant subtype, with incidence increasing alongside COVID-19 predisposing conditions.
  • Early diagnosis of RCM is vital for effective treatment and reducing morbidity/mortality.

Observation:

  • RCM presents with non-specific symptoms, often delaying diagnosis.
  • Common symptoms include orbital cellulitis, sinusitis, unilateral headache, diplopia, blurred vision, nasal congestion, epistaxis, and facial numbness.
  • Cranial nerve involvement, specifically facial nerve palsy, is an uncommon but serious complication.

Findings:

  • This case series reports three instances of facial nerve palsy in patients with COVID-19 associated mucormycosis.
  • These cases highlight a rare but significant neurological complication of RCM.
  • The findings contribute to the understanding of RCM's diverse clinical presentations.

Implications:

  • Increased awareness of RCM's non-specific symptoms and potential for cranial nerve involvement is needed.
  • Prompt diagnosis and aggressive treatment are essential for improving outcomes in RCM patients, particularly those with COVID-19.
  • Further research into the mechanisms and management of RCM-associated neurological complications is warranted.
Keywords:
covid-19diabetes mellitusfacial nerve palsymucormycosisrcm

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