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Updated: Aug 12, 2025

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Rectal Injury during Penile Inversion Vaginoplasty: An Algorithmic Approach to Prevention and Management
Martin P Morris1, Chien-Wei Wang2, Cole Holan3
1From the Sidney Kimmel Medical College at Thomas Jefferson University.
Background:
Penile inversion vaginoplasty (PIV) is a common procedure for transfeminine patients, with the goal of creating a functional vaginal canal and clitoris and a natural-appearing vulva. Creation of the neovagina requires opening of the prerectal space, most commonly from a perineal approach, and the reported rates of rectal perforation during this dissection range from 3% to 5%.
Methods:
Adult patients who underwent PIV at the authors' institution were identified retrospectively. Demographics, operative information, and postoperative clinical outcomes were extracted from the electronic medical record.
Results:
Ten of 146 patients (6.8%) experienced a rectal injury. All patients underwent an immediate repair (two-layer repair in eight patients, and three-layer repair in two), with two patients subsequently requiring temporary fecal diversion and two requiring muscle flaps (1.4% each). Literature review identified 18 relevant publications, with scarce in-depth analysis of management of initial rectal injuries.
Conclusion:
The authors' algorithmic approach to rectal injury during PIV is designed to facilitate decision-making based on preoperative preparation, consistent intraoperative monitoring, feasibility of primary repair of the rectum, and a multidisciplinary approach to longitudinal postoperative care.
Clinical Question/Level Of Evidence:
Therapeutic, IV.
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