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Discrepancy in Reporting of Perioperative Complications: A Retrospective Observational Study
Nuno V Gomes1,2, Amar Polutak3, Christian Schindler4
1Clinic for Anaesthesia, Intermediate Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland.
Objective:
To assess the discrepancy between perioperative complications, prospectively recorded during a cohort study versus retrospectively from health records.
Background:
Perioperative adverse events are relevant for patient outcome, but incomplete reporting is common.
Methods:
Two physicians independently recorded all intraoperative adverse events according to ClassIntra and all postoperative complications according to the Clavien-Dindo classification based on all available health records. These retrospective assessments were compared with the number and severity of those prospectively assessed in the same patients during their inclusion in 1 center of a prospective multicenter cohort study.
Results:
Interrater agreement between both physicians for retrospective recording was high [intraclass correlation coefficient: 0.89 (95% CI, 0.86, 0.91) for intraoperative and 0.88 (95% CI, 0.85, 0.90) for postoperative complications]. In 320 patients, the incidence rate was higher retrospectively than prospectively for any intraoperative complication (incidence rate ratio: 1.79; 95% CI, 1.50, 2.13) and for any postoperative complication (incidence rate ratio: 2.21; 95% CI, 1.90, 2.56). In 71 patients, the severity of the most severe intraoperative complication was higher in the retrospective than in the prospective data collection, whereas in 69 the grading was lower. In 106 patients, the severity of the most severe postoperative complication was higher in the retrospective than in the prospective data collection, whereas in 19 the grading was lower.
Conclusions:
There is a noticeable discrepancy in the number and severity of reported perioperative complications between these 2 data collection methods. On the basis of the double-blinded assessment of 2 independent raters, our study renders prospective underreporting more likely than retrospective overreporting.
Insights
Retrospective health record review identified more perioperative complications than prospective cohort study data. This suggests prospective data collection may underreport adverse events, impacting patient outcome analysis.
Area of Science:
- Medical research methodology
- Surgical outcomes analysis
- Patient safety
Background:
- Perioperative adverse events significantly impact patient outcomes.
- Incomplete reporting of these events is a common challenge in clinical studies.
- Accurate data collection is crucial for reliable outcome assessment.
Purpose of the Study:
- To evaluate discrepancies in perioperative complication reporting.
- Compare prospective cohort data with retrospective health record review.
- Determine potential biases in data collection methods for adverse events.
Main Methods:
- Two physicians independently assessed complications using ClassIntra and Clavien-Dindo classifications.
- Retrospective data extraction from health records was compared to prospective data.
- Analysis included incidence rates and severity grading of complications in 320 patients.
Main Results:
- Retrospective review revealed a higher incidence of both intraoperative (IRR 1.79) and postoperative complications (IRR 2.21).
- Severity grading of complications also showed discrepancies between prospective and retrospective data.
- High interrater agreement (ICC > 0.88) supported the reliability of retrospective assessment.
Conclusions:
- Significant discrepancies exist between prospective and retrospective perioperative complication reporting.
- Prospective data collection appears more prone to underreporting adverse events.
- Findings highlight the need for robust data capture in clinical research to ensure accurate patient outcome evaluation.
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