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Perioperative and Long-Term Outcome in Patients Treated for Jejunoileal Atresia

Henrik Røkkum1,2, Hanna Johannessen2, Kristin Bjørnland1,2

  • 1From the Department of Pediatric Surgery, Oslo University Hospital, Oslo, Norway.

Journal of Pediatric Gastroenterology and Nutrition
|February 2, 2023
PubMed

Insights

Jejunoileal atresia causes neonatal intestinal obstruction but most patients achieve excellent long-term gastrointestinal quality of life (QoL). Concomitant anomalies can impair outcomes, requiring ongoing management.

Area of Science:

  • Pediatric Surgery
  • Neonatal Medicine
  • Gastroenterology

Background:

  • Jejunoileal atresia is a frequent cause of intestinal obstruction in newborns.
  • Long-term outcome data for jejunoileal atresia patients are limited.
  • Understanding long-term gastrointestinal quality of life (QoL) is crucial for patient management.

Purpose of the Study:

  • To describe perioperative and postoperative outcomes in patients treated for jejunoileal atresia.
  • To evaluate the long-term gastrointestinal quality of life (QoL) in these patients.
  • To identify factors associated with long-term outcomes.

Main Methods:

  • A combined retrospective and cross-sectional observational study was conducted.
  • Perioperative data and complications (Clavien-Dindo classification) were recorded.
  • Long-term QoL was assessed using PedsQL Gastrointestinal Symptoms Scales and a custom questionnaire.

Main Results:

  • Seventy patients were included; 70% had primary anastomosis, 46% had concomitant anomalies.
  • Early complication rate was 66%, with 11% requiring reintervention; late reinterventions occurred in 21% for obstruction.
  • Overall mortality was 4%; 32 patients reported good long-term QoL, though concomitant anomalies correlated with poorer outcomes.

Conclusions:

  • Jejunoileal atresia involves significant initial morbidity but generally leads to excellent long-term outcomes.
  • Concomitant gastrointestinal anomalies are associated with impaired long-term QoL.
  • While most patients experience good QoL, specific issues like scar cosmesis and medication use warrant attention.
Abstract

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