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Salinomycin poisoning in horses.

J Rollinson1, F G Taylor, J Chesney

  • 1School of Veterinary Science, University of Bristol.

The Veterinary Record
|August 8, 1987
PubMed
Summary
This summary is machine-generated.

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Accidental salinomycin poisoning in horses, often from contaminated feed, causes varied signs like anorexia and ataxia. Horses are highly susceptible to ionophore toxicity, requiring consideration in differential diagnoses.

Area of Science:

  • Veterinary Toxicology
  • Equine Medicine

Background:

  • Ionophore compounds, like salinomycin and monensin, are used therapeutically in livestock.
  • Accidental poisoning can occur if these compounds contaminate equine feed.

Observation:

  • Six cases of accidental salinomycin poisoning in horses are presented.
  • Clinical signs were diverse, including anorexia, colic, weakness, and ataxia.
  • Serum biochemical profiles showed similarities to monensin poisoning.

Findings:

  • Horses exhibit a wide range of clinical signs following salinomycin poisoning.
  • Ionophore toxicity in horses presents with signs mimicking digestive and locomotory disorders.
  • Serum biochemistry can aid in diagnosing ionophore toxicity.

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Implications:

  • Salinomycin poisoning is a critical differential diagnosis for horses with unexplained clinical signs.
  • Equine susceptibility to ionophore toxicity necessitates careful feed management and monitoring.
  • Veterinarians should consider ionophore toxicity in horses housed at facilities using these compounds for other species.