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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
ACUTE POST-TRAUMATIC ENDOPHTHALMITIS SECONDARY TO BACILLUS PUMILUS / SAFENSIS
Tyler Etheridge1, Cole Swiston, Roger P Harrie
1John A. Moran Eye Center, University of Utah, Salt Lake City, Utah.
Purpose:
To report a case of post-traumatic endophthalmitis secondary to Bacillus pumilus/safensis .
Methods:
Observational case report of a single patient.
Results:
A 62-year-old man presented with a traumatic corneal laceration because of baling wire while working on a sheep farm. Appropriate corneal laceration repair with injection of intravitreal antibiotics (ceftazidime, clindamycin, and vancomycin) was performed. A single organism, identified as B. pumilus or Bacillus safensis, was isolated from the vitreous aspirate. A subsequent pars plana vitrectomy, pars plana lensectomy, anterior capsulotomy, and fluid-air exchange was required because of severe inflammatory reaction from retained lens material, retinal edema, and vitreous opacities. Vision improved from hand motion to 20/60 at the three-month follow-up visit.
Conclusion:
We describe a case of acute post-traumatic endophthalmitis secondary to B. pumilus/safensis.
Insights
A rare case of post-traumatic endophthalmitis caused by Bacillus pumilus/safensis occurred after a sheep farm injury. Prompt treatment improved vision, highlighting the importance of identifying unusual pathogens in eye infections.
Area of Science:
- Ophthalmology
- Microbiology
- Infectious Diseases
Background:
- Post-traumatic endophthalmitis is a severe intraocular infection following eye trauma.
- Ocular trauma can introduce various microorganisms, including bacteria, into the eye.
Observation:
- A 62-year-old male sustained a corneal laceration from baling wire on a sheep farm.
- The patient developed endophthalmitis, with vitreous aspirate identifying Bacillus pumilus or Bacillus safensis.
Findings:
- Initial management included corneal repair and intravitreal antibiotics.
- Severe inflammation necessitated pars plana vitrectomy, lensectomy, and fluid-air exchange due to retained lens material and retinal edema.
- Visual acuity improved from hand motion to 20/60 at three months post-treatment.
Implications:
- This case highlights Bacillus pumilus/safensis as a potential cause of post-traumatic endophthalmitis.
- Early diagnosis and aggressive management are crucial for visual recovery in such cases.
- Awareness of atypical bacterial pathogens in ocular infections is important for ophthalmologists.
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