Related Experiment Video

Updated: Aug 17, 2026

An Introduction to Worm Lab: from Culturing Worms to Mutagenesis
10:44

An Introduction to Worm Lab: from Culturing Worms to Mutagenesis

Published on: January 11, 2011

[Modifying effect of nutrition on the mutagenic activity of phosphorus and fluorine compounds]

Sh S Tazhibaev, E B Kozhakhmetova, K U Aldabergenova

    Voprosy Pitaniia
    |July 1, 1987
    PubMed

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    Covalently Linked Protein Regulators02:04

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    Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
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    In vitro Mutagenesis01:16

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    Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).