Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tinea: A concise synopsis.

Australian journal of general practice·2026
Same author

Breaking out: The wild world of diagnosing and managing drug eruptions.

Australian journal of general practice·2025
Same author

Isolated Immunoglobulin G4-Related Uveitis Diagnosed by Choroidal Biopsy.

Ophthalmic surgery, lasers & imaging retina·2025
Same author

Safety and Efficacy of Angiotensin Receptor Antagonists in Recessive Dystrophic Epidermolysis Bullosa.

The Australasian journal of dermatology·2025
Same author

An outbreak of reactive infectious mucocutaneous eruption (RIME) after Mycoplasma pneumoniae infections in Sydney, 2024: retrospective case series.

The Medical journal of Australia·2024
Same author

Impact of Biologic Therapy on Key Cardiovascular Risk Parameters in a Psoriatic Cohort-a Retrospective Review.

Dermatology and therapy·2024

Related Experiment Video

Updated: Aug 12, 2025

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

2.0K

SURGICAL DEMONSTRATION OF PRESSURE DIFFERENTIAL THROUGH AN OPTIC DISK PIT.

James C Rice1, Raoul P Scholtz, Joseph Joseph

  • 1Department of Ophthalmology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.

Retinal Cases & Brief Reports
|February 2, 2023
PubMed
Summary

This study demonstrates dynamic flow within an optic disk pit during surgery. Changes in intraocular pressure caused vitreous to move into and out of the pit, showing a pressure differential.

More Related Videos

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

3.1K
Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
06:09

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

1.7K

Related Experiment Videos

Last Updated: Aug 12, 2025

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
07:27

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance

Published on: August 25, 2021

2.0K
Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
08:55

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

3.1K
Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition
06:09

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

1.7K

Area of Science:

  • Ophthalmology
  • Retinal Surgery

Background:

  • Optic disk pits are congenital abnormalities.
  • The pathophysiology of optic disk pits and their communication with the vitreous or subarachnoid space remains incompletely understood.

Purpose of the Study:

  • To visualize and demonstrate intraoperative dynamic flow through an optic disk pit.
  • To provide evidence for the communication between the vitreous cavity and the optic nerve's perineural space.

Main Methods:

  • Retrospective interventional case report.
  • Standard 25-gauge pars plana vitrectomy.
  • Induction of posterior hyaloid separation with triamcinolone stain, temporal peripapillary laser, and sulfur hexafluoride (SF 6) gas injection.

Main Results:

  • Intraoperative observation of vitreous prolapsing into the optic disk pit with increased intraocular pressure.
  • Demonstration of vitreous being drawn back into the vitreous cavity as intraocular pressure was reduced.
  • Clear evidence of a pressure differential across the optic disk pit.

Conclusions:

  • Histological evidence supports communication between the vitreous cavity and the optic nerve's perineural space.
  • This case provides intraoperative visualization of dynamic flow through an optic disk pit.
  • The observed flow is influenced by intraocular pressure fluctuations.