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Related Experiment Video

Updated: Aug 11, 2025

Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
08:26

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[Development of Virtual-assisted Lung Mapping].

Masaaki Nagano1, Masaaki Sato, Jun Nakajima

  • 1Department of Thoracic Surgery, The University of Tokyo, Tokyo, Japan.

Kyobu Geka. the Japanese Journal of Thoracic Surgery
|February 2, 2023
PubMed
Summary

Virtual-assisted lung mapping (VALMAP) improves sublobar lung cancer resection. Novel techniques enhance nodule identification and surgical margin adequacy, reducing recurrence after segmentectomy.

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Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonary Medicine

Context:

  • Sublobar resection is gaining importance in early-stage lung cancer due to improved survival rates compared to lobectomy.
  • Local recurrence remains a significant concern following sublobar resection, often linked to inadequate surgical margins.
  • Accurate preoperative localization and margin assessment are crucial for successful sublobar lung cancer surgery.

Purpose:

  • To address the limitations of conventional virtual-assisted lung mapping (VALMAP 1.0) in identifying pulmonary nodules and ensuring adequate surgical margins.
  • To introduce and evaluate novel VALMAP techniques, including dual staining and proximal mapping with coils, for improved sublobar resection accuracy.
  • To enhance the safety and efficacy of sublobar lung cancer resection by optimizing preoperative marking and localization strategies.

Summary:

  • The study introduces advancements in virtual-assisted lung mapping (VALMAP) to overcome challenges in preoperative localization of pulmonary nodules for sublobar resection.
  • VALMAP dual staining, utilizing indigo carmine and indocyanine green (ICG), enhances the detection rate of markings during surgery.
  • VALMAP 2.0 incorporates a coil-based proximal mapping technique for 3D localization, improving accuracy for deep-seated tumors and ensuring adequate surgical margins.

Impact:

  • Improved detection rates and accuracy in marking pulmonary nodules, leading to more precise sublobar resections.
  • Enhanced ability to achieve adequate surgical margins, potentially reducing the risk of locoregional recurrence after segmentectomy.
  • VALMAP advancements offer a more reliable approach for minimally invasive lung cancer surgery, supporting the trend towards segmentectomy.