Related Experiment Video
Updated: Aug 11, 2025
Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
Published on: May 10, 2021
[Analysis of Surgical Margin Recurrence Following Segmentectomy for Early-stage Non-small Cell Lung Cancer]
Tatsuya Goto1, Mika Miyajima, Masaya Nakamura
1Division of Thoracic and Cardiovascular Surgery, Niigata University, Niigata, Japan.
Background:
Surgical margin recurrence following segmentectomy is a critical issue because it may have been avoided by lobectomy.
Methods:
Between January 2000 and December 2018, we retrospectively investigated 199 patients who underwent segmentectomy for c-StageⅠ non-small cell lung cancer at our hospital.
Results:
Recurrence occurred in 20 cases, of which 3 cases had surgical margin recurrence. In our previous study, the recurrence risk factor after segmentectomy was radiologic solid tumor size( cut-off value 1.5 cm). Of the 130 patients in the low-risk group with radiologic solid tumor size of less than 1.5 cm, five had any recurrence, three of which had surgical margin recurrence. In the high-risk group with radiologic solid tumor size of 1.5 cm or more, no surgical margin recurrence was observed. Three cases of surgical margin recurrence were accompanied by lepidic components, and the tumors were difficult to identify intraoperatively and were located close to adjacent areas.
Conclusion:
Surgical margin recurrence may be avoided by carefully considering the segments to be resected and improving the method for identifying the intersegmental plane.
Insights
Surgical margin recurrence after lung segmentectomy for non-small cell lung cancer is a concern. Careful segment selection and improved intersegmental plane identification can help avoid recurrence, especially in tumors with lepidic components.
Area of Science:
- Thoracic Surgery
- Surgical Oncology
- Pulmonary Medicine
Context:
- Segmentectomy for early-stage non-small cell lung cancer (NSCLC) is an alternative to lobectomy.
- Surgical margin recurrence after segmentectomy is a significant clinical problem.
- Identifying patients at risk for recurrence is crucial for optimizing treatment strategies.
Purpose:
- To investigate the incidence and risk factors for surgical margin recurrence after segmentectomy in patients with clinical Stage I NSCLC.
- To evaluate the relationship between radiologic solid tumor size and surgical margin recurrence.
- To identify characteristics of tumors associated with surgical margin recurrence.
Summary:
- A retrospective study of 199 patients undergoing segmentectomy for c-Stage I NSCLC identified 3 cases of surgical margin recurrence.
- Radiologic solid tumor size < 1.5 cm was associated with a higher risk of recurrence (3/5 cases), while tumors ≥ 1.5 cm showed no margin recurrence.
- Surgical margin recurrences were linked to lepidic components and intraoperative identification challenges near adjacent lung areas.
Impact:
- Findings suggest that careful selection of resected segments and enhanced methods for identifying intersegmental planes can potentially prevent surgical margin recurrence.
- This research aids in refining surgical techniques for segmentectomy in NSCLC, aiming to improve oncologic outcomes.
- Understanding tumor characteristics like lepidic components is vital for surgical planning and reducing recurrence risk.
More Related Videos
07:47Author Spotlight: 3D Scanning and Augmented Reality for Enhanced Cancer Surgery Communication
Published on: December 15, 2023
07:13Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
Published on: April 18, 2025