Related Experiment Video
Updated: Aug 11, 2025

Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Treatment of Advanced Kienböck's Disease Using 3D Printing Assisted Autologous Costochondral Transplantation: A Case
Zhenzhong Zhu1, Qian Tang1, Jia Xu1
1Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China.
Case:
We describe a patient with advanced Kienböck's disease, treated with 3-dimensional (3D) printing assisted costochondral transplantation. Cartilage shaping was achieved according to a biomimetic 3D-printed prosthesis designed by mirror symmetry of the healthy wrist. The inserted cartilage spacer was fixed using the autologous palmar longus tendon. After 14 months of follow-up, the patient had significant pain relief and had recovered nearly the full range of wrist motion. No significant absorption or osseous metaplasia of the cartilage was seen on the radiographic and magnetic resonance images.
Conclusion:
This costochondral transplantation strategy may offer a feasible treatment option for patients with severe Kienböck's disease.

