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Possible Mpox Protection from Smallpox Vaccine-Generated Antibodies among Older Adults

Iván Sanz-Muñoz, Laura Sánchez-dePrada, Javier Sánchez-Martínez

Emerging Infectious Diseases

|February 2, 2023

Abstract:

Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71-80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.

Keywords:

Spain antibodies immunosenescence monkeypox mpox sexually transmitted infections smallpox vaccine vaccinia viruses zoonoses

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