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Updated: Aug 11, 2025

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
Published on: October 25, 2013
Carbazole-Derived Amphiphile-Based AIEgen: Detection of Nitro-Antibiotics and Water-Repelling Surfaces
Sagnik De1, Oiyao Appun Pegu1, Gopal Das1
1Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Abstract:
We have designed three amphiphilic substituted urea compounds with varying chain lengths. These hydrophobic amphiphiles displayed aggregation-induced emission on solvent switching. The aggregates were further detailed by microscopy. The hydrophobicity of these AIEgens has been used to create water-repelling fluorescent surfaces. The AIEgen via the photoinduced electron transfer-mediated mechanism has been applied in the detection of nitroantibiotics. The analytical utility of the AIEgen is being demonstrated concerning the detection of nitroantibiotics in biofluids.
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