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Updated: Aug 11, 2025

Laparoscopy-endoscopy Cooperative Surgery for the Treatment of Gastric Gastrointestinal Stromal Tumors
Published on: February 19, 2022
[Laparoscopic Surgery for Gastric Gastrointestinal Stromal Tumors]
Shinya Otsuka1, Joichirou Horii, Ryousuke Hamano
1Dept. of Gastroenterological Surgery, National Hospital Organization Fukuyama Medical Center.
Abstract:
Gastric gastrointestinal stromal tumors(GISTs)are rarely accompanied by lymph node metastasis; therefore, laparoscopic partial gastrectomy is feasible for managing GISTs. Between 2005 and 2022, 60 patients underwent open or laparoscopic surgery for preoperatively suspected or histopathologically confirmed GISTs. Tumors were detected in the upper, mid, and lower stomach in 38, 18, and 4 patients, respectively. Intraluminal tumors or those with a mixed tumor growth pattern were identified in 42 patients, whereas tumors with an extraluminal growth pattern were noted in 18 patients. Open and laparoscopic surgery was performed in 28 and 32 patients, respectively. The adaptation for laparoscopic surgery was less than 5 cm in size. The laparoscopic approaches were as follows: conventional wedge resection in 19 patients, transillumination and serosal dissection method in 3, laparoscopic and endoscopic cooperative surgery in 8, and gastrectomy in 2 patients. Compared with the open surgery group, the laparoscopic surgery group presented a significant reduction in operation time, estimated blood loss, tumor size, and length of postoperative hospitalization. Based on the modified-Fletcher clinicopathological risk classification, 49, 6, and 5 patients were categorized into the low- or very low-, mid-, and high-risk groups, respectively. Recurrence was only observed in the open surgery group. The 10-year survival rates were 100% in both groups. The 5-year recurrence-free survival rates were 100 and 87% in the laparoscopic and open surgery groups, respectively. The aforementioned laparoscopic approaches were associated with favorable surgical outcomes.
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