[Successful Treatment with TACE and RFA for a Hepatocellular Carcinoma Case with Lung Metastasis]

Area of Science:

• Hepatobiliary Malignancies
• Interventional Radiology
• Oncology

Context:

• Hepatocellular carcinoma (HCC) recurrence with extrahepatic metastasis presents a treatment challenge.
• Standard molecular therapies were interrupted due to adverse events.
• Lung metastasis in specific segments (S1+2, S6) required targeted intervention.

Purpose:

• To report a successful treatment strategy for HCC with isolated lung metastasis.
• To evaluate the efficacy of transarterial chemoembolization (TACE) and percutaneous radiofrequency ablation (RFA) in managing lung metastases.
• To demonstrate a minimally invasive approach for complex metastatic disease.

Summary:

• A patient with ruptured HCC initially treated with TACE and liver resection developed lung metastases.
• Transarterial chemoembolization (TACE) was performed for bilateral lung metastases, with careful attention to arterial supply to avoid spinal cord complications.
• Percutaneous radiofrequency ablation (RFA) was subsequently applied to residual viable S6 lesion, achieving complete tumor necrosis in both lung metastases.

Impact:

• This case highlights the potential of combined TACE and RFA as an effective treatment for selected cases of HCC with limited lung metastasis.
• Successful management of extrahepatic disease progression despite interrupted systemic therapy.
• Demonstrates the feasibility and effectiveness of interventional radiology techniques in managing complex oncological scenarios.