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Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
[Effect of hypertensive gestosis on the condition of the fetus]
1Klinik für Gynäkologie und Geburtshilfe des Bereichs Medizin Karl-Marx-Universität Leipzig.
In a retrospective study fetal risk was investigated in 138 pregnant women with hypertensive gestosis was investigated by means of selected parameters. We used the patho-physiologic classification and divided the patients in the groups of preeclampsia and chronic hypertension. By this it is possible to show in preeclampsia a larger shore of premature infants and a latent deficient fetal development. There is no significant difference of the average duration of pregnancy between the two groups. The gestosis symptoms of hypertension and proteinuria show differences with regard to their pathogenetic value. Correlative analyses between blood pressure values and proteinuria show predominantly inverse relations to pregnancy duration, birth weight of the newborn and pH-values in the umbilical artery post partum. On the other hand, they cannot be demonstrated in chronic hypertension. The results are being discussed in connection with possibly occurring differences of cardiocirculatory parameters and uteroplacental perfusion in either group of gestosis.
In a retrospective study fetal risk was investigated in 138 pregnant women with hypertensive gestosis was investigated by means of selected parameters. We used the patho-physiologic classification and divided the patients in the groups of preeclampsia and chronic hypertension. By this it is possible to show in preeclampsia a larger shore of premature infants and a latent deficient fetal development. There is no significant difference of the average duration of pregnancy between the two groups. The gestosis symptoms of hypertension and proteinuria show differences with regard to their pathogenetic value. Correlative analyses between blood pressure values and proteinuria show predominantly inverse relations to pregnancy duration, birth weight of the newborn and pH-values in the umbilical artery post partum. On the other hand, they cannot be demonstrated in chronic hypertension. The results are being discussed in connection with possibly occurring differences of cardiocirculatory parameters and uteroplacental perfusion in either group of gestosis.
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