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Muir-Torre Syndrome: Abdominal Sebaceous Carcinoma.

An Bui¹, Shalini Shah², Nutan Winston²

¹Surgery, Riverside Community Hospital, Riverside, USA.

|February 3, 2023

Summary

This summary is machine-generated.

A 56-year-old male presented with a rapidly growing abdominal mass, later diagnosed as sebaceous carcinoma. This rare cancer, potentially linked to Muir-Torre syndrome, highlights the importance of vigilant cancer screening.

Keywords:

abdominal cystic mass muir torre syndrome muir-torre syndrome sebaceous carcinoma sebaceous gland

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Published on: December 19, 2019

Area of Science:

Oncology
Dermatology
Genetics

Background:

A 56-year-old male with a history of neurological conditions and prior surgeries presented with a large, rapidly growing left lower quadrant abdominal mass.
The mass had been present for a year, with recent rapid growth and ulceration, discharging blood and pus.

Observation:

The patient denied systemic symptoms such as fever or chills, but reported a significant family history of cancers, including early-onset colorectal cancer.
Imaging and biopsy revealed a dermal neoplasm with specific cellular characteristics, including lobular growth and sebaceous differentiation.

Findings:

Pathological examination confirmed sebaceous carcinoma, a rare malignancy.
The findings raised suspicion for Muir-Torre syndrome, a hereditary cancer predisposition syndrome.

Implications:

This case underscores the importance of considering rare genetic syndromes like Muir-Torre syndrome in patients with sebaceous carcinoma, especially with a relevant family history.
Multidisciplinary follow-up with oncology and gastroenterology is crucial for comprehensive management and screening.