Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Response01:28

Inflammatory Response

3.8K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
3.8K
NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

7.8K
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...
7.8K
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

169
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
169
Inflammation01:38

Inflammation

54.3K
Overview
54.3K
Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

109
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
109
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF01:24

Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF

205
Tumor Necrosis Factor (TNF), a proinflammatory cytokine, contributes significantly to the inflammation seen in Crohn's disease. It exists as soluble TNF and membrane-bound TNF, with actions mediated through TNF receptors (TNFR). TNFR activation leads to the release of proinflammatory cytokines, T-cell activation, collagen production, and leukocyte migration, all contributing to inflammation in Crohn's disease. Anti-TNF monoclonal antibodies, namely infliximab (Remicade), adalimumab...
205

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

The Correlation between Erythrocyte Sedimentation Rate and C-reactive Protein Ratio, and Lipid Profile in Dyslipidemia Patients with Dry Eye Disease.

Recent advances in inflammation & allergy drug discovery·2026
Same journalSame Topic

Pharmacological Characterization of Digera muricata Ethanolic Extract in a Rodent Model of Hepatotoxicity.

Recent advances in inflammation & allergy drug discovery·2026
Same journal

Effect of Hydrogen-rich Water on Chronic Kappa-carrageenan-induced Colitis in Weaned Female Swiss Albino Mice: A Preliminary Study.

Recent advances in inflammation & allergy drug discovery·2026
Same journal

Renoprotective Mechanisms of SGLT2 Inhibitors: Integrating Clinical and Experimental Evidence from Inflammation to Fibrosis.

Recent advances in inflammation & allergy drug discovery·2026
Same journal

Effects of Vitamin D Supplementation on Serum Levels and Gene Expression of IL-10 and IL-35 Among Women with Unexplained Recurrent Spontaneous Abortion.

Recent advances in inflammation & allergy drug discovery·2026
Same journal

Effect of Helicobacter pylori Eradication on Disease Symptoms, Inflammation, and Quality of Life in Patients with Rheumatoid Arthritis: A Non-blinded Prospective Quasi-experimental Study.

Recent advances in inflammation & allergy drug discovery·2026

Related Experiment Video

Updated: Aug 11, 2025

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

12.5K

Nano-Phytopharmaceuticals in Inflammation.

Akhila Sivasankaran Nair1, Remya Kopilakkal2

  • 1Department of Pharmacognosy, KVM College of Pharmacy, Cherthala, Alappuzha (Dist.), Kerala, 688527, India.

Recent Advances in Inflammation & Allergy Drug Discovery
|February 3, 2023
PubMed
Summary

Topical nano-phytopharmaceuticals offer enhanced anti-inflammatory effects by improving herbal drug delivery. This approach overcomes limitations of synthetic drugs and traditional herbal remedies for better therapeutic outcomes.

Keywords:
Nano-phytopharmaceuticalsanti-inflammatory drugsimmunosuppressant drugsnon-steroidal anti-inflammatory drugsphyto nanovesiclestopical nano phytopharmaceuticals

More Related Videos

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

2.6K
A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents
04:19

A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents

Published on: April 19, 2019

21.3K

Related Experiment Videos

Last Updated: Aug 11, 2025

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

12.5K
Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
11:44

Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B

Published on: January 19, 2022

2.6K
A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents
04:19

A New Best Practice for Validating Tail Vein Injections in Rat with Near-infrared-Labeled Agents

Published on: April 19, 2019

21.3K

Area of Science:

  • Pharmacology
  • Nanotechnology
  • Natural Products

Background:

  • Inflammation is a natural defense but can lead to chronic disorders.
  • Synthetic anti-inflammatory drugs (NSAIDs, corticosteroids) have significant side effects and limitations.
  • Traditional herbal medicines show promise but also have limitations in efficacy and delivery.

Purpose of the Study:

  • To review research on topical nanophytopharmaceuticals for anti-inflammatory activity.
  • To evaluate the potential of nanotechnology in enhancing herbal drug delivery.
  • To explore nano-formulations as an alternative to synthetic anti-inflammatory agents.

Main Methods:

  • Compilation and analysis of existing research studies on topical nanophytopharmaceuticals.
  • Focus on studies demonstrating anti-inflammatory activity.
  • Evaluation of nano-formulation impact on drug penetration, distribution, and efficacy.

Main Results:

  • Nano-formulation significantly increases the penetration and distribution of phytopharmaceuticals.
  • Topical nanophytopharmaceuticals demonstrate enhanced anti-inflammatory efficacy compared to conventional forms.
  • Evidence supports improved therapeutic outcomes with nano-delivery systems.

Conclusions:

  • Topical nanophytopharmaceuticals represent a promising strategy for managing inflammation.
  • Nanotechnology overcomes limitations of both synthetic drugs and traditional herbal medicines.
  • This approach facilitates targeted local and systemic delivery of active phytoconstituents.