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Oncology Clinical Trials in Greece: Progress in the Past Decade
Maria Eleni Ourailidou1, Alexandra Tsirigoti2, Georgia Kotsira2
1Pharmaceutical Studies & Research Division, Clinical Trials Department, National Organization for Medicines, Athens, Greece.
Journal of Long-Term Effects of Medical Implants
|February 3, 2023
Summary
Greek oncology clinical trials advanced cancer research over the past decade. Research focused on lung cancer and multiple myeloma treatments, with ongoing efforts to improve patient survival and quality of life.
Area of Science:
- Oncology
- Clinical Research
- Drug Development
Background:
- Cancer poses a significant global health burden, necessitating continuous research for improved treatments.
- Recent scientific advancements have enhanced cancer prevention, screening, and therapeutic strategies.
Purpose of the Study:
- To evaluate the progress and identify challenges in oncology clinical trials conducted in Greece between 2010 and 2020.
- To analyze the landscape of cancer research within Greece over the past decade.
Main Methods:
- A systematic search of the EU Clinical Trials Register was performed using the terms 'cancer' and 'Greece'.
- Data analysis focused on oncology trials approved in Greece from 2010 to 2020.
Main Results:
- A total of 480 oncology clinical trials were approved in Greece during the study period.
- The majority were multinational, phase III trials investigating lung cancer and multiple myeloma treatments.
- Small-molecules and monoclonal antibodies targeting key pathways were frequently evaluated, with many leading to new therapies.
Conclusions:
- Greek oncology research has actively contributed to developing effective and tolerable anticancer agents.
- Future research directions include novel trial designs, improved patient outcomes, and enhanced globalization of clinical research.
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