Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.4K
Blood Flow01:29

Blood Flow

70.6K
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
70.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Benefit of Percutaneous Treatment of Fontan Pathway Obstructions.

Journal of clinical medicine·2026
Same author

Incidental Hepatic Findings in Cardiac Magnetic Resonance Imaging Examinations in Patients with Congenital Heart Disease: A Pilot Study.

Journal of clinical medicine·2026
Same author

Towards fully automated synthetic ECV quantification: an open-access machine learning-based approach for fast blood draw-free CMR.

Scientific reports·2026
Same author

Strain Analysis from Transverse CMR Cine Imaging in Congenital Heart Disease: Feasibility, Reproducibility, and Comparison to Global Longitudinal Strain.

Healthcare (Basel, Switzerland)·2026
Same author

Uncertainty Quantification in Hemodynamic Metrics from 4D Flow MRI with Super-resolution in a Carotid Bifurcation Model.

Journal of imaging informatics in medicine·2026
Same author

Wall shear stress and oscillatory shear index are independently associated with complicated carotid artery plaques.

European heart journal. Cardiovascular Imaging·2025

Related Experiment Video

Updated: Aug 11, 2025

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.4K

Population-based reference values for 4D flow MRI derived aortic blood flow parameters.

Marie Schafstedde1,2,3,4, Lina Jarmatz1, Jan Brüning1,4

  • 1Institute of Congenital Heart Disease, German Heart Center Charité, Berlin, Germany.

Physiological Measurement
|February 3, 2023
PubMed
Summary
This summary is machine-generated.

Older individuals exhibit distinct thoracic aorta blood flow patterns, with higher normalized flow displacement and angle, and lower wall parallelism and area. These findings establish age- and sex-specific reference values for 4D flow cardiovascular magnetic resonance (CMR) analysis.

Keywords:
4D flow MRIaortablood flowcardiovascular magnetic resonancehemodynamicspopulationreference values

More Related Videos

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
08:42

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

Published on: October 22, 2014

27.4K
Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
06:04

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

Published on: September 27, 2024

1000

Related Experiment Videos

Last Updated: Aug 11, 2025

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

3.4K
Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
08:42

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research

Published on: October 22, 2014

27.4K
Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
06:04

Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome

Published on: September 27, 2024

1000

Area of Science:

  • Cardiovascular Imaging
  • Biomedical Engineering
  • Physiology

Background:

  • Age-related changes in cardiovascular health are significant.
  • Understanding thoracic aorta hemodynamics is crucial for diagnosing cardiovascular diseases.
  • 4D flow cardiovascular magnetic resonance (CMR) offers advanced insights into blood flow dynamics.

Purpose of the Study:

  • To investigate age-related variations in thoracic aorta blood flow profiles.
  • To establish age- and sex-specific reference values for thoracic aorta hemodynamics using 4D flow CMR.
  • To correlate blood flow parameters with aortic geometry.

Main Methods:

  • 126 healthy volunteers (aged 20-80 years, 51% female) underwent 4D flow CMR.
  • 12 analysis planes in the thoracic aorta were defined for quantitative assessment.
  • Key parameters evaluated included normalized flow displacement (NFD), wall parallelism (WPD), and flow angles (α).

Main Results:

  • Significant age-related differences were observed in the ascending aorta.
  • Older subjects showed increased NFD and flow angles, and decreased WPD and A80.
  • Blood flow parameters correlated with the cross-sectional aortic area; no significant sex differences were found.

Conclusions:

  • Age influences thoracic aorta blood flow patterns, particularly in the ascending aorta.
  • The study provides novel age- and sex-specific reference values for 4D flow CMR analysis.
  • These reference values may aid in future clinical studies of aortic flow profiles.