Multifaceted role of cardiovascular biomarkers
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Updated: Aug 11, 2025
Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
1Department of Cardiovascular Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.
Insights
Cardiovascular disease (CVD) biomarkers aid early detection and prevention. Novel, non-invasive biomarkers improve diagnosis and risk assessment, including for COVID-19 patients.
Area of Science:
- Biochemistry
- Cardiology
- Medical Diagnostics
Background:
- Cardiovascular diseases (CVDs) are a leading global health concern.
- Late-stage diagnosis often necessitates heart transplantation.
- Early detection through risk identification and preventive measures is crucial.
Purpose of the Study:
- To review various categories of cardiovascular biomarkers.
- To emphasize novel biomarkers for CVD diagnosis and prognosis.
- To discuss the utility of biomarkers in identifying cardiovascular complications in COVID-19 patients.
Main Methods:
- Literature review of cardiovascular biomarker research.
- Categorization of existing and novel biomarkers.
- Analysis of biomarker applications in CVD and COVID-19.
Main Results:
- Biomarkers are critical for early CVD diagnosis and risk stratification.
- Recent discoveries include more specific and sensitive biomarkers.
- Non-invasive biomarkers offer an advantage for assessing pathophysiological status.
Conclusions:
- Biomarkers are essential tools for managing cardiovascular diseases.
- Novel biomarkers enhance diagnostic accuracy and prognostic capabilities.
- Biomarkers play a role in identifying high-risk COVID-19 patients for cardiovascular complications.
Abstract:
Cardiovascular diseases, a global health issue, claim the lives of many every year. Lifestyle changes and genetic predisposition are the key drivers for the development of CVDs. In many of the patients, the disease is detected at the end stage making heart transplantation the only treatment option. Hence every attempt should be made to identify the risk at an early stage and initiate preventive measures to improve the quality of their life. Biomarkers are one of the critical factors that aid in the early diagnosis of CVDs. More specific and highly sensitive biomarkers have been discovered lately and have been employed for prognosis and diagnosis of CVDs. The present review briefs about the various categories of cardiovascular biomarkers with emphasis on novel biomarkers and discusses the biomarkers employed for different purposes in CVDs. The biomarkers have also helped in identifying COVID-19 patients with increased risk for developing cardiovascular complications. Being non-invasive makes biomarkers advantageous over other methods for evaluating the pathophysiological status of CVDs.
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