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Updated: Aug 11, 2025
Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
Published on: September 10, 2018
Evaluation of acceptability, safety, and continuation rates of centchroman as postabortion nonsteroidal contraceptive
Kavita Agarwal1, Rupali Dewan1
1Department of Obstetrics and Gynaecology, VMMC & Safdarjung Hospital, New Delhi, India.
Objectives:
To evaluate acceptability, safety, and continuation rates of centchroman following abortion.
Study Design:
Prospective, observational study. Following spontaneous/induced abortion, women were offered centchroman, 30-mg tablet twice weekly for first 3 months, then once weekly with 1 year of follow-up.
Results:
Of 120 women who opted for centchroman, continuation rate was 91% at 12 months. There was one case of user failure and one method failure and 26% had infrequent cycles.
Conclusions:
Centchroman is safe, effective, has good acceptance, and continuation rate post abortion with infrequent menstrual cycles as the main limiting factor for its continuation.
Implications:
Centchroman, available in Government scheme for contraception, has good acceptance and continuation rate post abortion. Its inclusion in contraceptive choices offered for postabortion contraception can go a long way in spacing of pregnancies, decreasing repeated unintended pregnancies, unsafe abortions, maternal morbidity, and mortality.
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