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Updated: Aug 11, 2025

07:34
FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
36.9K
Addressing ethical issues related to prenatal diagnostic procedures
1Department of Obstetrics and Gynecology, Makerere University College of Health Sciences, Kampala, Uganda. dankkaye@yahoo.com.
Maternal Health, Neonatology and Perinatology
|February 4, 2023
Summary
Preimplantation genetic testing (PGT) screens embryos for genetic mutations, offering reassurance for advanced maternal age and high-risk couples. However, careful consideration of its risks, costs, and ethical implications is crucial for patient selection and decision-making.
Area of Science:
- Reproductive Medicine
- Clinical Genetics
- Embryology
Background:
- Preimplantation genetic testing (PGT) aids women of advanced maternal age and high-risk couples by screening embryos for genetic mutations.
- This technology can improve embryo selection, increase implantation rates, and reduce miscarriage rates in assisted reproductive technology (ART).
- However, PGT involves embryo risks, additional costs, and raises questions about routine implementation.
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