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Implications for COVID-19 vaccine uptake: A systematic review
Peter Adu1, Tosin Poopola1, Oleg N Medvedev2
1School of Health, Wellington Faculty of Health, Victoria University of Wellington, New Zealand.
Journal of Infection and Public Health
|February 4, 2023
Summary
Understanding COVID-19 vaccine hesitancy is key to increasing vaccination coverage. Addressing safety concerns and providing clear information are crucial for boosting vaccine uptake globally.
Area of Science:
- Public Health
- Epidemiology
- Vaccinology
Background:
- Global COVID-19 vaccination coverage is hampered by significant vaccine hesitancy.
- Understanding the drivers of vaccine uptake is essential for effective national vaccination programs.
- This review synthesizes evidence on COVID-19 infodemics and predictors of vaccination uptake.
Approach:
- Systematic review of 12,502 peer-reviewed articles retrieved from seven databases (July 2021-March 2022).
- Included 57 articles meeting selection criteria.
- Analyzed determinants of COVID-19 vaccine uptake before and after US FDA vaccine approval.
Key Points:
- Decreased vaccine hesitancy correlated with increased COVID-19 vaccine uptake.
- Concerns regarding vaccine safety, side effects, rapid development, and effectiveness fueled hesitancy.
- Post-FDA approval, fear of injections and insufficient information were primary drivers of hesitancy.
Conclusions:
- Vaccination programs must address safety and effectiveness concerns.
- Providing comprehensive vaccine information and pandemic impact details is vital.
- Reassurance on vaccine safety and exploring needle-free alternatives can enhance uptake.
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