Related Experiment Video
Updated: Aug 11, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Developing an interprofessional team to support patients prescribed long-term high-dose opioid therapy
Michael P Conley1,2, Abigail T Elmes1,2, John R Roberts2
1Department of Pharmacy and Health Systems Sciences, Northeastern University, Boston, MA, USA.
An interprofessional team effectively reduced high-dose opioid (HDO) use in primary care. This approach supported safer pain management, decreasing daily morphine milligram equivalents (MME) for patients on long-term HDO.
Area of Science:
- Pain Management
- Pharmacology
- Public Health
Background:
- Opioid prescribing rates remain high despite decreases, with daily morphine milligram equivalents (MME) significantly elevated compared to 1999.
- Long-term high-dose opioid (HDO) use presents significant risks, necessitating specialized management strategies.
Purpose of the Study:
- To evaluate the effectiveness of an interprofessional team (IPT) in managing adults prescribed long-term HDO (exceeding 50 daily MME).
- To support safer, evidence-based pain management through patient education and individualized care planning.
Main Methods:
- An interprofessional team (IPT) comprising a clinical pharmacist, addiction nurse, medical director, and physician/NP managed patients on long-term HDO.
- Patient visits focused on education regarding HDO risks and pain management strategies.
- Care planning included opioid tapers, non-opioid pain medications (NOPM), non-pharmacological therapy (NPT), and naloxone co-prescribing.
Main Results:
- The IPT successfully engaged 90% of eligible patients.
- Excluding outliers, the cohort showed an average 18% decrease in daily MME.
- Commonly utilized NOPM included acetaminophen, NSAIDs, and pregabalin; NPT included physical, aquatic, and behavioral therapies.
Conclusions:
- An IPT model is effective in reducing daily MME for patients on long-term HDO.
- Shared decision-making, collaborative teamwork, and patient-centered goals are crucial for transitioning patients to safer, evidence-based pain management.
- This approach facilitates safer opioid management in primary care settings like Federally Qualified Health Centers.
More Related Videos
09:29Investigating Drivers of Antireward in Addiction Behavior with Anatomically Specific Single-Cell Gene Expression Methods
Published on: August 4, 2022
09:54Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
Published on: March 8, 2020
Related Concept Videos
Interdisciplinary Care: The Health Care Team-II
Physical Therapist
A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
Analgesia and Pain Management
Chronic Kidney Disease III: Interprofessional Care
Interdisciplinary Care: The Health Care Team-I
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution...
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Documentation in Long-Term and Home Healthcare Setting
Long-Term Care Facilities