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Sexually Transmitted Infections & the Heart
Kiera Liblik1, Jeffrey Lam1, Alex Pham2
1Department of Medicine, Kingston Health Sciences Centre, Queen's University, Kingston, ON, Canada.
Insights
Sexually transmitted infections (STIs) significantly impact cardiovascular (CV) health, increasing morbidity and mortality globally. This review summarizes STIs
Area of Science:
- Public Health
- Infectious Diseases
- Cardiology
Background:
- Sexually transmitted infections (STIs) cause significant global morbidity and mortality.
- Cardiovascular (CV) disease is a leading cause of death and disability worldwide.
- STIs can negatively affect CV health and exacerbate existing CV conditions, disproportionately impacting marginalized populations.
Purpose of the Study:
- To review and synthesize current knowledge on the relationship between STIs and CV health.
- To highlight STIs with known CV implications.
- To discuss diagnostic and treatment strategies for managing STIs and their CV consequences.
Main Methods:
- Comprehensive literature review of studies examining STIs and cardiovascular health.
- Identification of specific STIs with documented CV effects.
- Analysis of diagnostic and therapeutic approaches.
Main Results:
- Multiple STIs, including syphilis, HIV, HPV, HSV, hepatitis B and C, CMV, chlamydia, gonorrhea, and trichomoniasis, are linked to CV health issues.
- Untreated STIs and their CV complications pose a greater burden on vulnerable populations.
- Existing data linking STIs and compromised CV health requires further summarization and integration.
Conclusions:
- STIs represent a significant, often overlooked, risk factor for cardiovascular disease.
- Understanding the CV implications of STIs is crucial for comprehensive patient care and public health strategies.
- Further research and integrated management approaches are needed to address the dual burden of STIs and CV disease.
Abstract:
Sexually transmitted infections (STIs) have substantial morbidity and mortality worldwide, with over 1 million new infections occurring daily. Similarly, cardiovascular (CV) disease is the leading global cause of death and has tremendous impact on disability as well as quality of life. Several STIs have potential CV consequences and may precipitate reoccurrence of underlying CV comorbidity. Notably, untreated STIs and associated CV complications have an increased impact on marginalized individuals and those with limited access to health resources and care. Syphilis, human immunodeficiency virus, human papillomavirus, herpes simplex virus, hepatitis B, hepatitis C, cytomegalovirus, chlamydia, gonorrhea, and trichomoniasis have been identified as having CV implications. Yet, the data linking compromised CV health and STIs have not previously been summarized. The present review encapsulates the current knowledge surrounding the impacts of STIs on CV health as well as diagnostic and treatment strategies.
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