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Updated: Aug 11, 2025
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Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging
Published on: March 14, 2025
280
Cognitive Neuroscience of Obsessive-Compulsive Disorder
Laura B Bragdon1, Goi Khia Eng1, Nicolette Recchia1
1Department of Psychiatry, New York University School of Medicine, One Park Avenue, 8th floor, New York, NY 10016, USA; Nathan S. Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA.
The Psychiatric Clinics of North America
|February 5, 2023
Summary
Neuroimaging studies reveal key brain mechanisms in obsessive-compulsive disorder (OCD). Understanding these neural processes can improve treatments and develop new interventions for OCD patients.
Area of Science:
- Cognitive Neuroscience
- Neuroimaging
- Psychiatry
Background:
- Obsessive-compulsive disorder (OCD) is a complex mental health condition.
- Understanding the neurobiological underpinnings of OCD is crucial for effective treatment.
- Existing research highlights the role of various brain circuits in OCD.
Purpose of the Study:
- To provide an updated review of neuroimaging studies in OCD.
- To examine findings across seven key neurocognitive domains.
- To contextualize neuroimaging results within OCD phenomenology and treatment.
Main Methods:
- Systematic review of published neuroimaging research.
- Analysis of studies focusing on cognitive functions in OCD patients.
- Synthesis of findings related to brain activity and structure.
Main Results:
- Neuroimaging studies identify specific alterations in brain regions associated with OCD.
- Consistent patterns emerge across different neurocognitive domains.
- These findings link neural mechanisms to observable OCD symptoms.
Conclusions:
- Cognitive neuroscientific research offers valuable insights into OCD's neurobiology.
- Enhanced understanding of neural mechanisms can optimize current OCD treatments.
- This knowledge may guide the development of innovative therapeutic strategies for OCD.
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