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Published on: June 15, 2019
Septic bursitis in immunocompromised patients
1Department of Medicine, University of Wisconsin Hospital and Clinics, Madison 53792.
Abstract:
A retrospective analysis of 29 patients with septic bursitis was undertaken to ascertain if immunocompromised patients differed in their clinical presentations, type of organisms cultured, and outcome when compared with their non-immunocompromised cohorts. Thirty episodes of septic bursitis occurred in 29 patients, 43 percent of which occurred in immunocompromised patients. Despite similar clinical presentations, the bursae of immunocompromised patients took three times longer to sterilize and had a much higher bursal white blood cell count when compared with the bursae of non-immunocompromised patients. The bacteriologic spectrum was essentially identical in both groups; there were no cases in which gram-negative organisms were recovered from infected bursae. No cases of septic bursitis were seen in neutropenic patients. The most common factors contributing to an immunocompromised state were alcoholism or steroid therapy. A successful resolution of septic bursitis was seen in all the patients in the immunocompromised groups.
Insights
Immunocompromised patients with septic bursitis showed delayed healing and higher white blood cell counts, though bacterial causes were similar. All patients achieved successful outcomes, highlighting effective septic bursitis treatment.
Area of Science:
- Infectious Diseases
- Rheumatology
- Immunology
Background:
- Septic bursitis is an infection of the bursa, a fluid-filled sac that acts as a cushion.
- Immunocompromised individuals may experience different disease trajectories and outcomes.
Purpose of the Study:
- To compare clinical presentations, causative organisms, and treatment outcomes of septic bursitis in immunocompromised versus non-immunocompromised patients.
Main Methods:
- Retrospective analysis of 29 patients with 30 episodes of septic bursitis.
- Comparison of clinical data, microbial cultures, and treatment responses between immunocompromised and non-immunocompromised groups.
Main Results:
- 43% of septic bursitis episodes occurred in immunocompromised patients.
- Immunocompromised patients had significantly longer sterilization times (3x) and higher bursal white blood cell counts.
- Bacteriology was similar between groups; no gram-negative organisms were identified.
- Alcoholism and steroid therapy were common predisposing factors in the immunocompromised group.
Conclusions:
- While clinical presentations are similar, immunocompromised patients experience prolonged septic bursitis resolution.
- Effective treatment strategies lead to successful outcomes in all patients, irrespective of immune status.
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