Recent advances of antioxidant low-dimensional carbon materials for biomedical applications

Nan Tang1,2, Zhen Ding1,2, Jin Zhang2

  • 1Department of Orthodontics, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, China.

Insights

Low-dimensional carbon nanomaterials offer potent antioxidant protection against cellular damage from reactive oxygen and nitrogen species. This review highlights their advancements, challenges, and biomedical applications.

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Oxidative Stress Research

Background:

  • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause significant cellular damage, contributing to various diseases.
  • Antioxidative nanomaterials are developed to mitigate oxidative stress and protect biological components like lipids, proteins, and DNA.
  • Low-dimensional carbon nanomaterials are emerging as promising antioxidants due to their nanoscale properties.

Purpose of the Study:

  • To provide an overview of recent advancements in antioxidant low-dimensional carbon materials.
  • To classify carbon nanomaterials based on their dimensional nanostructure (0D, 1D, 2D).
  • To discuss the challenges and future perspectives for these materials in biomedical fields.

Main Methods:

  • Literature review of recent studies on low-dimensional carbon nanomaterials.
  • Classification of carbon nanomaterials by dimensionality (zero, one, and two dimensions).
  • Analysis of physicochemical properties and antioxidant capabilities.

Main Results:

  • Low-dimensional carbon nanomaterials exhibit significant antioxidant activity.
  • These materials are categorized into zero-dimensional, one-dimensional, and two-dimensional nanostructures.
  • Unique physicochemical properties contribute to their high performance.

Conclusions:

  • Low-dimensional carbon nanomaterials represent a high-performance class of antioxidants.
  • Further research is needed to address challenges for clinical applications.
  • These materials hold great potential for biomedical fields and therapeutic uses.