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Updated: Jun 29, 2026

Fabrication of 3D Carbon Microelectromechanical Systems C-MEMS
Published on: June 17, 2017
Recent advances of antioxidant low-dimensional carbon materials for biomedical applications
Nan Tang1,2, Zhen Ding1,2, Jin Zhang2
1Department of Orthodontics, Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, School and Hospital of Stomatology, Jilin University, Changchun, China.
Abstract:
As the primary cause of many tissue damage and diseases, reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well known to be extremely harmful to a variety of biological components in cells including lipids, proteins and DNA. Numerous antioxidative nanomaterials have been artificially designed and rationally synthesized to protect cells from the oxidative damage caused by reactive oxygen species/reactive nitrogen species. Recent studies demonstrate that low dimensional carbon antioxidative nanomaterials have received a lot of attention owing to their tiny nanoscales and unique physicochemical property. As a result, a brief overview of recent advancements in antioxidant low-dimensional carbon materials is provided. Typically, carbon nanomaterials are classified according to their nanostructure dimensions, which are zero-dimension, one-dimension, and two-dimension. Last but not least, the challenges and perspectives of these high-performance low-dimensional materials in biomedical fields and further clinical usages are discussed as well.
Insights
Low-dimensional carbon nanomaterials offer potent antioxidant protection against cellular damage from reactive oxygen and nitrogen species. This review highlights their advancements, challenges, and biomedical applications.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Oxidative Stress Research
Background:
- Reactive oxygen species (ROS) and reactive nitrogen species (RNS) cause significant cellular damage, contributing to various diseases.
- Antioxidative nanomaterials are developed to mitigate oxidative stress and protect biological components like lipids, proteins, and DNA.
- Low-dimensional carbon nanomaterials are emerging as promising antioxidants due to their nanoscale properties.
Purpose of the Study:
- To provide an overview of recent advancements in antioxidant low-dimensional carbon materials.
- To classify carbon nanomaterials based on their dimensional nanostructure (0D, 1D, 2D).
- To discuss the challenges and future perspectives for these materials in biomedical fields.
Main Methods:
- Literature review of recent studies on low-dimensional carbon nanomaterials.
- Classification of carbon nanomaterials by dimensionality (zero, one, and two dimensions).
- Analysis of physicochemical properties and antioxidant capabilities.
Main Results:
- Low-dimensional carbon nanomaterials exhibit significant antioxidant activity.
- These materials are categorized into zero-dimensional, one-dimensional, and two-dimensional nanostructures.
- Unique physicochemical properties contribute to their high performance.
Conclusions:
- Low-dimensional carbon nanomaterials represent a high-performance class of antioxidants.
- Further research is needed to address challenges for clinical applications.
- These materials hold great potential for biomedical fields and therapeutic uses.

