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Updated: Aug 11, 2025

Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
Cytomegalovirus induced genital ulcer in human immunodeficiency virus positive patient
Kavya K Shree1, Sachin Somashekar1, Eswari Loganathan1
1Department of Dermatology and Venereology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Abstract:
Cytomegalovirus (CMV) can cause life-threatening disease in immunocompromised patients, such as those with human immunodeficiency virus. It is a rare but important cause of ulceration in the female genital tract. Although cutaneous manifestations are rare, there are growing reports of CMV infections in genital and perigenital ulcers in immunocompromised individuals. CMV disease of the female genital tract may result in significant morbidity, with fever, pain, bleeding, and superinfection, and it may be associated with the development of pelvic inflammatory disease and cervical intraepithelial neoplasia. There are several options for diagnosis and for safe treatment.
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