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Outcomes in Pediatric Endoscopic Skull Base Surgery: A Systematic Review
Erin M Lopez1, Zainab Farzal1, Kelly M Dean1
1Department of Otolaryngology-Head and Neck Surgery, University of North Carolina Memorial Hospitals, Chapel Hill, North Carolina, United States.
Journal of Neurological Surgery. Part B, Skull Base
|February 6, 2023
Summary
Endoscopic skull base surgery in children shows promise but faces challenges. Postoperative cerebrospinal fluid leaks and meningitis are key concerns, highlighting the need for standardized reporting in pediatric cases.
Area of Science:
- Neurosurgery
- Pediatric Surgery
- Otolaryngology
Background:
- Endoscopic skull base surgery is increasingly utilized in pediatric patients.
- A systematic review is needed to evaluate outcomes in this population.
Purpose of the Study:
- To systematically review the literature on endoscopic skull base surgery outcomes in pediatric patients (0-18 years).
- To identify common pathologies, surgical techniques, and complications.
Main Methods:
- Systematic literature review of PubMed and SCOPUS (2000-2020) adhering to PRISMA guidelines.
- Inclusion of case series with >10 pediatric patients undergoing endoscopic skull base surgery.
- Analysis of patient demographics, pathology, reconstruction, and surgical complications.
Main Results:
- 12 studies with 399 pediatric patients met inclusion criteria.
- Cerebrospinal fluid (CSF) leak was the most common pathology and postoperative complication.
- Postoperative meningitis occurred in 12 cases, with 2 fatalities.
Conclusions:
- Endoscopic skull base surgery is feasible for various pediatric conditions.
- Inconsistent data reporting hinders comparative analysis and meta-analyses.
- Standardized reporting is crucial for advancing research in rare pediatric skull base pathologies.
