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Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Kidney Transplant I: Introduction01:28

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A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Related Experiment Video

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A Modified Surgical Technique for Kidney Transplantation in Mice
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Nephron-sparing surgery for Wilms tumor.

Andrew J Murphy1,2, Andrew M Davidoff1,2

  • 1Department of Surgery, St. Jude Children's Research Hospital, Memphis, TN, United States.

Frontiers in Pediatrics
|February 6, 2023
PubMed
Summary

Radical nephroureterectomy is unsuitable for bilateral Wilms tumors. Nephron-sparing surgery is recommended for synchronous bilateral Wilms tumors to preserve kidney function and avoid renal insufficiency.

Keywords:
Wilms tumorbilateralkidneynephron-sparing surgerypartial nephrectomypediatric

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Area of Science:

  • Pediatric Oncology
  • Surgical Oncology
  • Nephrology

Background:

  • Radical nephroureterectomy, a standard for unilateral Wilms tumor, is not applicable to synchronous bilateral renal masses.
  • Bilateral Wilms tumors necessitate a tailored surgical strategy to preserve renal function.
  • Renal insufficiency is a significant risk in children with bilateral Wilms tumors.

Purpose of the Study:

  • To review the technical aspects of nephron-sparing surgery for synchronous bilateral Wilms tumor.
  • To discuss advancements in surgical adjuncts for bilateral Wilms tumor management.
  • To explore the role of nephron-sparing surgery in unilateral Wilms tumor cases.

Main Methods:

  • Review of surgical techniques for nephron-sparing surgery in bilateral Wilms tumor.
  • Discussion of pre-operative 3D imaging and fluorescence-guided surgery.
  • Analysis of outcomes for nephron-sparing approaches in Wilms tumor.

Main Results:

  • Nephron-sparing surgery is crucial for preserving renal parenchyma in synchronous bilateral Wilms tumors.
  • Advanced imaging and surgical guidance enhance tumor resection while minimizing damage.
  • The principles of nephron-sparing surgery may extend to unilateral Wilms tumor management.

Conclusions:

  • Nephron-sparing surgery is the preferred approach for synchronous bilateral Wilms tumors to prevent renal insufficiency.
  • Technological advancements are improving the efficacy and safety of these procedures.
  • Further research into the application of nephron-sparing techniques for Wilms tumors is warranted.