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Effects of using in-line bacterial filters with continuous positive airway pressure devices in patients with sleep

Satoshi Hamada1, Jumpei Togawa2, Hironobu Sunadome2

  • 1Department of Advanced Medicine for Respiratory Failure, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Respiratory Investigation
|February 6, 2023
PubMed

Insights

In-line bacterial filters for CPAP machines did not affect sleep-disordered breathing control. While some patients perceived pressure changes, the filters did not alter apnea-hypopnea index, indicating no impact on SDB management.

Area of Science:

  • Respiratory Medicine
  • Sleep Medicine
  • Medical Device Technology

Background:

  • Philips Respironics recommended in-line bacterial filters for continuous positive airway pressure (CPAP) devices in June 2021 due to a recall.
  • The clinical impact of using these in-line filters with CPAP devices remained unexamined.

Purpose of the Study:

  • To evaluate the effects of in-line bacterial filters on CPAP therapy in patients with sleep-disordered breathing (SDB).
  • To assess patient perceptions of CPAP pressure when using in-line filters.
  • To determine if in-line filters influence SDB control as measured by the apnea-hypopnea index.

Main Methods:

  • Retrospective evaluation of 160 patients with SDB who voluntarily used in-line bacterial filters.
  • Patient perceptions of CPAP pressure were collected through verbal interviews.
  • Apnea-hypopnea index (AHI) data from CPAP devices before and after filter use were analyzed.

Main Results:

  • A significant portion of patients reported perceived changes in CPAP pressure: 8.1% felt it was very weak, 26.2% somewhat weak, 64.4% unchanged, and 1.3% somewhat strong.
  • Among those perceiving very weak pressure, 38.5% discontinued filter use.
  • No significant change in the apnea-hypopnea index was observed after using in-line filters (n=129, p=0.85).

Conclusions:

  • In-line bacterial filters may alter subjective patient perception of CPAP pressure.
  • These filters do not appear to impact the objective control of sleep-disordered breathing as indicated by the apnea-hypopnea index.
  • The use of in-line filters in CPAP therapy for SDB requires further investigation regarding patient adherence and objective efficacy.
Keywords:
Continuous positive airway pressureDeviceIn-line bacteria filterRecallSleep disordered breathing

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