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Updated: Aug 11, 2025

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
Published on: February 25, 2022
[The pituitary gland unveiled: from the stimulation-secretion coupling to cellular networks wiring]
1Institut de Génomique Fonctionnelle, Université de Montpellier, CNRS, INSERM, 141 rue de la Cardonille, 34094 Montpellier Cedex 5, France.
Abstract:
The year 2021 ended with an event of great sadness: the death of Andrée Tixier-Vidal. She was not only a pioneer in cell biology but also the charismatic promoter of stimulating and successful multidisciplinary collaborations. Her achievements led to subsequent major discoveries on both the stimulation-secretion coupling of pituitary endocrine cells and the hitherto unknown organization of these cells into multicellular 3D networks which build-up highly organized pulses of pituitary hormones controlling basic body functions such as growth and reproduction.
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