Related Experiment Video
Updated: Aug 11, 2025

A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy
Published on: July 12, 2021
Variability in Resource Utilization in the Evaluation and Management of Simple Febrile Seizures Inpatients in US
Dane Saksa1, Lena S Sun2, Jonathan Rodean3
1David Geffen School of Medicine at UCLA, 10833 Le Conte Ave, Los Angeles, CA.
Insights
Hospitalized simple febrile seizure (SFS) patients often undergo unnecessary evaluations like MRI and EEG. Resource utilization varied widely across hospitals, with no clear factors explaining these differences.
Area of Science:
- Pediatric Neurology
- Healthcare Resource Utilization
- Clinical Practice Variation
Background:
- Simple febrile seizures (SFS) are common in young children.
- Evaluation and treatment protocols for hospitalized SFS patients can vary.
- Understanding resource use is crucial for optimizing pediatric healthcare.
Purpose of the Study:
- To characterize resource utilization in the evaluation and treatment of hospitalized SFS patients.
- To identify variations in the use of MRI, EEG, and anticonvulsants.
- To examine hospital-level differences in managing SFS.
Main Methods:
- Retrospective cohort study using the Pediatric Health Information System (2010-2015).
- Included inpatients aged 6 months to 5 years with SFS diagnosis.
- Compared resource utilization (MRI, EEG, anticonvulsants) between patient groups and across hospitals.
Main Results:
- 8.4% of SFS patients presenting to the ED were hospitalized.
- Over half (57.8%) of hospitalized SFS patients received no further MRI/EEG or anticonvulsant treatment.
- Significant inter-hospital variation was observed in MRI, EEG, and anticonvulsant utilization rates.
Conclusions:
- Wide variation exists in resource utilization for hospitalized SFS patients.
- No specific hospital-level factors were identified to explain this variation.
- Further research may be needed to understand and standardize SFS management.
Objective:
To characterize resource utilization in the evaluation and treatment of hospitalized simple febrile seizure (SFS) patients in US tertiary pediatric hospitals.
Methods:
This is a retrospective cohort study using the Pediatric Health Information System from 2010 to 2015. Children 6 months to 5 years of age who were inpatients with a diagnosis of SFS. Children who had brain magnetic resonance imaging (MRI), electroencephalography (EEG), or received anticonvulsants were compared with those who did not have testing or anticonvulsant treatment. Hospital-level variation in the utilization rates of MRI, EEG, or treatment with anticonvulsants was also evaluated.
Results:
In Pediatric Health Information System-participating institutions, 8.4% (n=3640) of children presenting to the emergency department with SFS were hospitalized. Among these SFS inpatients, 57.8% (n= 2104) did not receive further evaluation with MRI/EEG or treatment with anticonvulsants. There was evidence of wide inter-hospital variation in resource utilization rates. The median (interquartile range) utilization rate was 6.2% (3.0 to 11.0%) for MRI, 28.5% (16.0 to 46.3%) for EEG and 17.1% (10.9 to 22.3%) for treatment with anticonvulsants.
Conclusion:
No specific hospital-level factors were identified that contributed to the variation in resource utilization in the evaluation and management of hospitalized SFS patients.
More Related Videos
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
09:57Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
Related Concept Videos
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Antiepileptic Drugs: Modulators of Neurotransmitter Release Mediated by SV2A Protein
SV2A is a transmembrane glycoprotein located predominantly in the brain, modulating the release of neurotransmitters for neuronal communication. Both levetiracetam and brivaracetam exhibit a high affinity for...
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Increased Body Temperature
Patterns of Fever