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Obstructive sleep apnea and vitamin D level: Has the dust settled?
Huai Heng Loh1,2, Norlela Sukor2
1Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.
The Clinical Respiratory Journal
|February 6, 2023
Summary
Obstructive sleep apnea (OSA) and vitamin D deficiency are linked to serious health issues. This review clarifies the unclear relationship between OSA and vitamin D, exploring potential connections and future research directions.
Area of Science:
- Sleep Medicine
- Endocrinology
- Public Health
Background:
- Obstructive sleep apnea (OSA) is a prevalent sleep disorder.
- Vitamin D deficiency is a widespread nutritional issue.
- Both conditions are linked to increased morbidity and mortality.
Purpose of the Study:
- To review current evidence on the relationship between OSA and vitamin D deficiency.
- To explore potential biological mechanisms connecting these conditions.
- To identify gaps and opportunities for future research.
Main Methods:
- Narrative review of existing clinical studies and literature.
- Analysis of contradictory findings in current research.
- Synthesis of evidence regarding potential links.
Main Results:
- The relationship between OSA and vitamin D deficiency is complex and not fully understood.
- Conflicting results exist in clinical studies.
- Potential mechanisms include inflammation, hormonal pathways, and lifestyle factors.
Conclusions:
- Further research is needed to elucidate the precise relationship between OSA and vitamin D.
- Understanding this link may lead to improved management strategies for both conditions.
- Investigating therapeutic interventions targeting vitamin D in OSA patients is warranted.
Keywords:
apnea hypopnea indexcholecalciferolcontinuous positive airway pressurehypoxiaobesitysleep disordersMore Related Videos
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