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Related Experiment Video

Updated: Aug 11, 2025

A Multi-detection Assay for Malaria Transmitting Mosquitoes

A Multi-detection Assay for Malaria Transmitting Mosquitoes

Published on: February 28, 2015

Engineered Antiviral Sensor Targets Infected Mosquitoes.

Elena Dalla Benetta¹, Adam J López-Denman², Hsing-Han Li¹

¹School of Biological Sciences, Department of Cell and Developmental Biology, University of California, San Diego, La Jolla, CA, 92093, USA.

Biorxiv : the Preprint Server for Biology

|February 7, 2023

Summary

This summary is machine-generated.

A new antiviral strategy called REAPER (RNA Expression Activates Poisonous Effector Ribonuclease) uses CRISPR Cas13 to target and destroy arboviruses in mosquitoes, reducing disease transmission.

Keywords:

CRISPR/Cas Cas13d RNA-knockdown mosquitoes

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Last Updated: Aug 11, 2025

A Multi-detection Assay for Malaria Transmitting Mosquitoes

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Published on: February 28, 2015

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Alphavirus Transducing System: Tools for Visualizing Infection in Mosquito Vectors

Alphavirus Transducing System: Tools for Visualizing Infection in Mosquito Vectors

Published on: November 24, 2010

Area of Science:

Molecular Biology
Genetics
Vector-borne Diseases

Background:

Vector-borne diseases pose significant global health risks due to escalating burdens.
Innovative tools are critical for targeting disease-carrying mosquitoes.
Existing methods for controlling mosquito-borne illnesses require novel strategies.

Conclusions:

REAPER is an effective antiviral strategy against arboviruses in mosquitoes.
This technology significantly reduces viral replication and transmission.
REAPER represents a promising addition to molecular genetic tools for combating mosquito-borne diseases.