Related Experiment Videos
Isolation and characterization of the glutathione-elliptinium conjugate in human urine
A Gouyette1, E Voisin, C Auclair
1Service de Pharmacologie Clinique, Institut Gustave-Roussy, Villejuif, France.
Anticancer Research
|July 1, 1987
Abstract:
In a cancer patient given 100 mg/m2 elliptinium by intravenous infusion, the glutathione conjugate was found in urine. This metabolite was isolated after ion-exchange treatment and high performance liquid chromatography. Its structure was assessed by fast-atom bombardment mass spectrometry and comparison with an authentic sample.