Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cyproheptadine in anorexia nervosa.

S C Goldberg, K A Halmi, E D Eckert

    The British Journal of Psychiatry : the Journal of Mental Science
    |January 1, 1979
    PubMed
    Summary

    Cyproheptadine effectively promoted weight gain in a specific subgroup of anorexia nervosa patients. This finding is crucial for understanding treatment responses in severe anorexia nervosa cases.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Cytokine production in patients with anorexia nervosa, bulimia nervosa, and obesity.

    The International journal of eating disorders·2000
    Same author

    Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial.

    Lancet (London, England)·2000
    Same author

    A preliminary report on pain thresholds in bulimia nervosa during a bulimic episode.

    Comprehensive psychiatry·1999
    Same author

    Elevated pain threshold in anorexia nervosa subjects.

    Biological psychiatry·1999
    Same author

    Leptin in anorexia nervosa.

    The Journal of clinical endocrinology and metabolism·1998
    Same author

    Treatment of bulimia nervosa with ondansetron.

    Archives of general psychiatry·1997

    Area of Science:

    • Clinical Psychology
    • Psychiatry
    • Pharmacology

    Background:

    • Anorexia nervosa is a complex eating disorder with significant treatment challenges.
    • Identifying predictors of treatment response is crucial for optimizing patient care.

    Purpose of the Study:

    • To investigate the efficacy of cyproheptadine combined with behavior therapy in treating anorexia nervosa.
    • To identify patient subgroups that may benefit from cyproheptadine treatment.

    Main Methods:

    • Randomized controlled trial involving 81 female patients with anorexia nervosa.
    • Four treatment arms: cyproheptadine + behavior therapy, cyproheptadine + no behavior therapy, placebo + behavior therapy, placebo + no behavior therapy.

    Main Results:

    • Cyproheptadine demonstrated effectiveness in inducing weight gain for a specific subgroup.
    • This subgroup was characterized by a history of birth complications, significant weight loss (41-52%), and prior treatment failure.
    • These characteristics may indicate a more severe form of anorexia nervosa.

    Conclusions:

    • Cyproheptadine can be a valuable therapeutic option for a select group of anorexia nervosa patients.
    • Further research is warranted to explore the mechanisms behind this differential treatment response.
    • This study highlights the importance of personalized medicine approaches in eating disorder treatment.

    Related Experiment Videos