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Updated: Aug 11, 2025

High-resolution Single Particle Analysis from Electron Cryo-microscopy Images Using SPHIRE
Published on: May 16, 2017
Xiang Geng1,2, Andong Liu2, Yan'an Chen3
1School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China.
This study introduces an accelerated area-reconstruction h-dome transform algorithm to prevent over-segmentation in particle image analysis. The enhanced method significantly improves processing speed for accurate segmentation of irregularly shaped particles.
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