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Updated: Aug 11, 2025

Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
A stepwise external cardioversion protocol for atrial fibrillation to maximize acute success rate
Yousef Darrat1, Steve Leung2, Liliane Elayi1
1Cardiac Electrophysiology Department, Saint Joseph Hospital, 1401 Harrodsburg Road, Lexington, KY 40504, USA.
A new stepwise cardioversion protocol for persistent atrial fibrillation (AF) achieved over 99% success, safely restoring sinus rhythm. This effective AF treatment protocol is suitable for both inpatient and outpatient settings.
Area of Science:
- Cardiology
- Electrophysiology
Background:
- Persistent atrial fibrillation (AF) management often requires cardioversion.
- Existing protocols for failed external electrical cardioversion are not well-defined.
Purpose of the Study:
- To evaluate the efficacy of a pre-defined stepwise cardioversion protocol for persistent AF (≤12 months duration).
- To determine the success rate and safety of the proposed protocol.
Main Methods:
- A stepwise protocol involving electrode placement, expiratory compression, and dual defibrillator energy was applied.
- 414 patients with persistent AF (≤12 months) were included.
Main Results:
- An overall success rate of 99.3% was achieved in restoring sinus rhythm.
- Only 12.5% of patients required multiple cardioversion attempts.
- High body mass index predicted the need for multiple attempts; high transthoracic impedance correlated with failed cardioversion.
- No major complications were reported.
Conclusions:
- The stepwise cardioversion protocol demonstrates a high success rate (>99%) for persistent AF.
- The protocol is safe for use in both outpatient and inpatient settings.
- This approach offers an effective rhythm management strategy for AF patients.
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