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Published on: July 27, 2018
ICTV Virus Taxonomy Profile: Matonaviridae 2022
Annette Mankertz1, Min-Hsin Chen2, Tony L Goldberg3
1Department of Infectious Diseases, Robert Koch-Institute, 13353 Berlin, Germany.
Abstract:
The family Matonaviridae comprises enveloped viruses with positive-sense RNA genomes of 9.6-10 kb. The genus Rubivirus includes rubella virus (species Rubivirus rubellae) infecting humans, ruhugu virus (species Rubivirus ruteetense) infecting bats and rustrela virus (species Rubivirus strelense) infecting rodents and zoo animals. Rubella virus is spread via droplets. Postnatal infection leads to benign disease with rash and fever. Infection of seronegative women with rubella virus during the first trimester of pregnancy will often result in severe foetal malformations, known as congenital rubella syndrome. Vaccines are globally available. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Matonaviridae, which is available at ictv.global/report/matonaviridae.
Insights
The Matonaviridae family includes rubella virus, a droplet-spread pathogen causing congenital rubella syndrome in infants. Vaccines are available to prevent this significant public health concern.
Area of Science:
- Virology
- Microbiology
- Public Health
Background:
- The Matonaviridae family consists of enveloped viruses with positive-sense RNA genomes.
- The genus Rubivirus encompasses rubella virus (infecting humans), ruhugu virus (bats), and rustrela virus (rodents/zoo animals).
Purpose of the Study:
- To summarize the International Committee on Taxonomy of Viruses (ICTV) report on the family Matonaviridae.
- To provide an overview of the classification, characteristics, and public health implications of viruses within this family.
Main Methods:
- This study is a summary of the official ICTV report.
- Information is compiled from the ICTV's established taxonomic framework.
Main Results:
- Rubella virus, a member of the genus Rubivirus, is transmitted via droplets.
- Postnatal rubella infection typically causes a mild illness, but can lead to severe congenital rubella syndrome in infants if contracted by pregnant women.
- Effective vaccines for rubella virus are widely accessible globally.
Conclusions:
- The Matonaviridae family, particularly the Rubivirus genus, represents significant viral pathogens.
- Understanding the taxonomy and transmission of these viruses is crucial for public health strategies and disease prevention, including vaccination.
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